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Hydrocortisone is available with or without a prescription. Low-strength preparations (0.5% or 1%) are used without a prescription for the temporary relief of (1) minor skin irritations, itching, and rashes caused by eczema, insect bites, poison ivy, poison oak, poison sumac, soaps, detergents, cosmetics, and jewelry; (2) itchy anal and rectal areas; and (3) itching and irritation of the scalp. It is also used to relieve the discomfort of mouth sores.Hydrocortisone may be prescribed by your doctor to relieve the itching, redness, dryness, crusting, scaling, inflammation, and discomfort of various skin conditions; the inflammation of ulcerative colitis or proctitis; or the swelling and discomfort of hemorrhoids and other rectal problems.Hydrocortisone comes as ointment, cream, lotion, liquid, gel, medicated cloth towelette, and spray for use on the skin; foam, suppositories, cream, ointment, and enema for rectal use; and paste for use in the mouth.Hydrocortisone is usually used one to four times a day for skin problems.For mouth sores, it usually is applied two or three times a day after meals and at bedtime. If mouth sores do not begin to heal within 7 days, call your doctor.For colitis, hydrocortisone usually is used every night or twice a day (every morning and night) for 2 or 3 weeks. Although colitis symptoms may improve within 3-5 days, 2-3 months of regular enema use may be required. Call your doctor if your colitis symptoms do not improve within 3 weeks.For proctitis, hydrocortisone usually is used one or two times a day for 2-3 weeks, then if necessary every other day until your condition improves. Proctitis symptoms may improve within 5-7 days.For hemorrhoids, hydrocortisone usually is used twice a day (every morning and night) for 2-6 days.Follow the directions on the label carefully, and ask your doctor or pharmacist to explain any part that you do not understand. Use hydrocortisone exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.If you obtained hydrocortisone without a prescription and your condition does not improve within 7 days, stop using it and call your doctor.Call your doctor if any area treated with hydrocortisone gets worse or if redness, swelling, or oozing of pus develops.To use hydrocortisone ointment, cream, lotion, liquid, or gel on your skin, wash or soak the affected area thoroughly before applying the medication, unless it irritates your skin. Then apply sparingly in a thin film and rub it in gently.To use the lotion, liquid, or gel on your scalp, part your hair, apply a small amount of the medicine on the affected area, and rub it in gently. Protect the area from washing and rubbing until the medication dries. You may wash your hair as usual but not right after applying the medicine.To apply the aerosol spray, shake well and spray on the affected area holding the container about 3-6 inches away. Spray for about 2 seconds to cover an area the size of your hand. Take care not to inhale the vapors. If you are spraying near your face, cover your eyes.Avoid prolonged use on the face, in the genital and rectal areas, and in skin creases and armpits unless directed to do so by your doctor.If you are using hydrocortisone on your face, keep it out of your eyes.If you are using hydrocortisone on a child=s diaper area, do not use tight-fitting diapers or plastic pants. Such use may increase side effects.Do not apply cosmetics or other skin preparations on the treated area without talking to your doctor. Chloroquine phosphate is in a class of drugs called antimalarials and amebicides. It is used to prevent and treat malaria. It is also used to treat amebiasis.Chloroquine phosphate comes as tablet to take by mouth. For prevention of malaria in adults, one dose is usually taken once a week on exactly the same day of the week. Your doctor will tell you how many tablets to take for each dose. One dose is taken beginning 2 weeks before traveling to an area where malaria is common, while you are in the area, and then for 8 weeks after you return from the area. If you are unable to start 2 weeks before traveling, your doctor may tell you to take double the dose right away.For treatment of acute attacks of malaria in adults, one dose is usually taken right away, followed by half the dose 6 to 8 hours later and then half the dose once a day for the next 2 days.For prevention and treatment of malaria in infants and children, the amount of chloroquine phosphate is based on the child's weight. Your doctor will calculate this amount and tell you how much chloroquine phosphate your child should receive.For treatment of amebiasis, one dose is usually taken for 2 days and then half the dose every day for 2 to 3 weeks. It is usually taken in combination with other amebicides.Chloroquine phosphate may cause an upset stomach. Take chloroquine phosphate with food.Chloroquine phosphate is used occasionally to decrease the symptoms of rheumatoid arthritis and to treat systemic and discoid lupus erythematosus, scleroderma, pemphigus, lichen planus, polymyositis, sarcoidosis, and porphyria cutanea tarda. Talk to your doctor about the possible risks of using this drug for your condition.
This product is able to be sourced and supplied at excellent prices because of favourable cross border currency conversions. All products are authentic brand names and will include a product information insert in English.Medical Information:Gonaphene tablets contain the active ingredient clomifene citrate (previously spelt clomiphene in the UK). (NB. Clomifene is also available without a brand name, ie as the generic medicine.)Clomifene works by causing an increase in the levels of hormones in the female body which control the development and release of an egg. These hormones are released from the pituitary gland in the brain and are known as follicle stimulating hormone (FSH) and luteinising hormone (LH). FSH stimulates the ovaries and LH causes the release of an egg from the ovaries (ovulation).Oestrogen normally causes the brain to stop releasing FSH and LH following ovulation, as part of the normal menstrual cycle. It does this by acting on receptors in a part of the brain called the hypothalamus, which sends messages to the pituitary gland.Clomifene works by blocking the oestrogen receptors in the hypothalamus. This stops oestrogen from acting on these receptors, and therefore stops the message being sent to the pituitary gland. This results in the release of more FSH and LH from the pituitary gland. The increase in these hormones increases the chances of egg development and ovulation.Clomifene is used to stimulate ovulation in women whose infertility is due to problems with ovulation.What is it used for? Infertility in women caused by failure of ovulation Medical Information:Insulin is a hormone that is produced in the body. It works by lowering levels of glucose (sugar) in the blood. Insulin aspart is a fast-acting form of insulin.Insulin aspart is used to treat type 1 (insulin-dependent) diabetes in adults. It is usually given together with another long-acting insulin.Insulin aspart (IN-su-lin AS-part)is a fast-acting type of human insulin. Insulin is used by people type 2 diabetes to help keep blood sugar levels under control. If you have type 2 diabetes, your body cannot make enough or does not use insulin properly. So, you must take additional insulin to regulate your blood sugar and keep your body healthy. This is very important as too much sugar in your blood can be harmful to your health. Since insulin aspart acts faster than regular human insulin, you normally should use insulin aspart with a longer-acting insulin.
Composition Sodium Carboxymethylcellulose 1.00 % w/w Sorbitol (as Sorbitol solution IP) 3.00 % w/w Potassium chloride IP 0.12 % w/w Sodium chloride IP 0.0844 % w/w Magnesium chloride IP 0.0052 % w/w Calcium chloride IP 0.0146 % w/w Potassium dihydrogen phosphate BP 0.0342 % w/w Description Aqwet is synthetic saliva. It is available as an aerosol spray in natural flavour. The volume contained in each aerosol can is 50 ml. It moistens the mucosa of the mouth, tongue and throat. It can be used as a replacement for natural saliva. It is more effective and long lasting than drinking or wetting the mouth with water or glycerol. Aqwet is an ozone freindly. Indications Aqwet can be used for dryness of the mouth or throat regardless of whether the condition is temporary or permanent. It is also used for intensive hygiene of the oral cavity and to help relieve bad taste. Dosage And Administration The can should always be held upright with the valve opening directed towards the mouth or throat. The nozzle should be pushed down for 1 to 2 seconds. Aqwet can be used as often as needed to maintain moistness. The valve opening should be cleaned if it becomes blocked. This product is able to be sourced and supplied at excellent prices because of favourable cross border currency conversions. All products are authentic brand names and will include a product information insert in English.Medical Information:Dilatrend lowers blood pressure and increases the output of the heart. It is prescribed for people with congestive heart failure to increase survival and reduce the need for hospitalization. Dilatrend may be prescribed if you have survived a heart attack and now suffer from left ventricular dysfunction, a condition where the left side of the heart no longer pumps properly. It is also used to control high blood pressure. It is often used with other drugs.Carvedilol is in a group of drugs called beta-blockers. Beta-blockers affect the heart and circulation (blood flow through arteries and veins).Carvedilol is used to treat heart failure and hypertension (high blood pressure). It is also used to treat or prevent heart attack.Treating high blood pressure or certain types of heart failure. It may also be used after a heart attack to improve survival in certain patients. It may be used along with other medicines. It may also be used for other conditions as determined by your doctor.Carvedilol is an alpha- and beta-blocker. It works by relaxing the blood vessels, slowing down the heart, and decreasing the amount of blood it pumps out. This decreases blood pressure, helps the heart pump more efficiently, and reduces the workload on the heart.
Spironolactone is used to treat certain patients with hyperaldosteronism (the body produces too much aldosterone, a naturally occurring hormone); low potassium levels; and in patients with edema (fluid retention) caused by various conditions, including heart, liver, or kidney disease. Spironolactone is also used alone or with other medications to treat high blood pressure. Spironolactone is in a class of medications called aldosterone receptor antagonists. It causes the kidneys to eliminate unneeded water and sodium from the body into the urine, but reduces the loss of potassium from the body.Furosemide, a 'water pill,' is used to reduce the swelling and fluid retention caused by various medical problems, including heart or liver disease. It is also used to treat high blood pressure. It causes the kidneys to get rid of unneeded water and salt from the body into the urine.Spironolactone/Furosemide comes as a tablet to take by mouth. It usually is taken once a day in the morning or sometimes twice a day . Take Lasilactone at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take spironolactone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.Your doctor may start you on a low dose of Lasilactone and gradually increase your dose. Lasilactone controls high blood pressure and hyperaldosteronism, but does not cure these conditions.. It may take about 2 weeks or longer before the full effect of spironolactone occurs. Continue to take spironolactone even if you feel well. Do not stop taking spironolactone without talking to your doctor.Lasilactone combination with other medicines to treat precocious puberty (a condition causing children to enter puberty too soon, resulting in the development of sexual characteristics in girls usually younger than 8 years of age and in boys usually younger than 9 years of age) or myasthenia gravis (MG, a disease in which the nerves do not function properly and patients may experience weakness; numbness; loss of muscle coordination; and problems with vision, speech, and bladder control). Lasilactone also may be used to treat certain female patients with abnormal facial hair. Talk to your doctor about the possible risks of using this medication for your condition. This product is able to be sourced and supplied at excellent prices because of favourable cross border currency conversions. All products are authentic brand names and will include a product information insert in English.Medical Information:Fluticasone (floo-TIK-a-sone) and salmeterol (sal-ME-te-role) is a combination of two medicines that are used to help control the symptoms of asthma and improve lung function. Long-term prevention and treatment of asthma and chronic lung diseases. It should not be used to treat a sudden symptom of shortness of breath (eg, sudden severe onset or worsening of wheezing, cough, chest tightness) because it does not work right away. It may also be used to treat other breathing conditions as determined by your doctor.Seretide Diskus is a combination "controller" medicine. It improves lung function and makes breathing easier by reducing airway swelling and irritation and by causing muscle relaxation. Fluticasone is a steroid. It prevents the release of substances in the body that cause inflammation. Salmeterol is a bronchodilator. It works by relaxing muscles in the airways to improve breathing.Fluticasone and salmeterol inhalation is used to prevent asthma attacks. Fluticasone and salmeterol inhalation is also used to treat chronic obstructive pulmonary disease (COPD) associated with chronic bronchitis.Maintenance treatment of asthma where use of combination product is appropriate (eg patients inadequately controlled with inhaled corticosteroids or patients stabilised on salmeterol and fluticasone) Severe COPD with repeated exacerbations inadequately controlled with regular beta2 agonist therapy.
This medication is used to prevent gout and gouty arthritis. It will not treat a sudden/severe attack of gout and may make it worse. Probenecid belongs to a class of drugs known as uricosurics. It lowers high levels of uric acid in your body by helping the kidneys to get rid of uric acid. When uric acid levels get too high, crystals can form in the joints, causing gout. Lowering uric acid levels may also help your kidneys.Probenecid is sometimes used along with penicillin antibiotics (e.g., penicillin, ampicillin, nafcillin) to increase antibiotic blood levels. This increase makes the antibiotic work better at treating certain infections. Probenecid works by decreasing the kidneys' ability to remove the antibiotic from the body.Probenecid should not be used in children younger than 2 years.How to use Probenecid OralTo prevent gout, take this medication by mouth, usually twice daily with food or antacids to reduce stomach upset or as directed by your doctor. It is best to drink a full glass of water with each dose and at least another 8 glasses (8 ounces each) a day while taking this drug in order to prevent kidney stones. If you are on restricted fluid intake, consult your doctor for further instructions. Your doctor may also instruct you on how to decrease acidity in your urine (e.g., avoid large amounts of ascorbic acid/vitamin C) to prevent kidney stones. Your doctor may order other medications (e.g., sodium bicarbonate, citrate) to make your urine less acidic.Dosage is based on your condition and response to therapy. Your doctor may direct you to take a low dose at first, then adjust your dose based on uric acid levels and your gout symptoms. After you have been symptom-free for several months and your uric acid levels are normal, your doctor may lower your probenecid dose to the lowest effective dose. Follow your doctor's directions carefully.Probenecid should not be started during a sudden/severe gout attack. Wait until your current attack is over before starting this medication. You may experience an increase in the number of gout attacks for several months after starting this medicine while the body removes extra uric acid. If you have a gout attack while taking probenecid, continue taking it along with your medications for gout pain.Probenecid is not a pain reliever. To relieve pain from gout, continue to take your medicines prescribed for pain from gout attacks (e.g., colchicine, ibuprofen, indomethacin) as directed by your doctor.If you are taking this medication to raise the level of antibiotics in your body, follow your doctor's directions for when to take the antibiotic and when to take the probenecid.Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.Inform your doctor if your condition persists or worsens. This product is able to be sourced and supplied at excellent prices because of favourable cross border currency conversions. All products are authentic brand names and will include a product information insert in English.Medical Information:This medication is used to treat sudden diarrhea (including traveler's diarrhea). It works by slowing down the movement of the gut. This decreases the number of bowel movements and makes the stool less watery. Loperamide is also used to reduce the amount of discharge in patients who have undergone an ileostomy. It is also used to treat on-going diarrhea in people with inflammatory bowel disease.Loperamide treats only the symptoms, not the cause of the diarrhea (e.g., infection). Treatment of other symptoms and the cause of the diarrhea should be determined by your doctor.Do not use in children younger than 6 years unless directed by your doctor. This medication should not be used in infants younger than 24 months.How to use Loperamide OralIf you are using the over-the-counter product to self-treat, read all the directions on the product package before taking this medication. If your doctor has prescribed this medication, follow your doctor's directions and the directions on your prescription label. If you have any questions, consult your doctor or pharmacist.Take this medication by mouth, usually after each loose stool, or as directed by your doctor. Dosage is based on your condition and response to therapy. In children, dosage is also based on age and weight. Adults should not use more than 8 milligrams in 24 hours if self-treating, or 16 milligrams if under a doctor's direction.Diarrhea can cause a serious loss of body water (dehydration). Drink plenty of fluids and minerals (electrolytes) to replace what is lost. Tell your doctor immediately if you develop signs of dehydration (e.g., extreme thirst, decreased urination, muscle cramps, weakness, fainting). You may also need to change to a bland diet during this time to reduce irritation to your stomach/intestines. Consult your doctor or pharmacist for more information.Tell your doctor if your diarrhea does not improve after 2 days, if your condition worsens, or if you develop new symptoms. If you develop blood in the stool, fever, or an uncomfortable fullness/swelling of the stomach/abdomen, or if you think you may have a serious medical problem, seek immediate medical attention.If you are taking this medication under your doctor's direction for ongoing diarrhea, tell your doctor if your diarrhea continues after 10 days of treatment. Rivastigmine is used to treat dementia (a brain disorder that affects the ability to remember, think clearly, communicate, and perform daily activities and may cause changes in mood and personality) in people with Alzheimer's disease (a brain disease that slowly destroys the memory and ability to think, learn, communicate and handle daily activities). Rivastigmine is also used to treat dementia in people with Parkinson's disease (a brain and nervous system disease with symptoms of slowing of movement, muscle weakness, shuffling walk, and loss of memory). Rivastigmine is in a class of medications called cholinesterase inhibitors. It improves mental function (such as memory and thinking) by increasing the amount of a certain natural substance in the brain.Rivastigmine comes as a capsule and solution (liquid) to take by mouth. It is usually taken twice a day with meals in the morning and evening. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take rivastigmine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.Your doctor will start you on a low dose of rivastigmine and slowly increase your dose, not more than once every 2 weeks.Rivastigmine may improve the ability to think and remember or slow the loss of these abilities, but does not cure Alzheimer's disease or dementia in people with Parkinson's disease. Continue to take rivastigmine even if you feel well. Do not stop taking rivastigmine without talking to your doctor.Rivastigmine oral solution may be swallowed directly from the syringe or mixed with a liquid before use. Mix it with a small glass of water, cold fruit juice, or soda. Be sure to stir the mixture completely. Do not mix this medication with any liquid other than the ones listed. If the medication is mixed with water, juice, or soda, it must be taken within 4 hours.Rivastigmine is also used sometimes to treat Lewy body dementia (a condition in which the brain develops abnormal protein structures, and the brain and nervous system are destroyed over time).
Nix Dermal Cream is indicated for the treatment of scabies and crab lice. Treatment of scabies:Adults and children over 2 years old should apply the cream to the skin over the whole body including the palms and soles, but not the head and face. Pay particular attention to the areas between the fingers and toes (including under the finger and toe nails), wrists, arm-pits, external genitals and buttocks. Babies and children under 2 years old should be treated as above and also have their necks, faces, ears and scalps treated. Avoid the area around the mouth (as the cream could be licked off) and around the eyes. Children between 2 months and 2 years should only be treated under medical supervision.Elderly (over 65 years old) should apply as directed for adults and children over 2 years old but should also include their necks, faces, ears and scalps. Care must be taken to avoid applying Dermal Cream to areas close to the eyes.The cream should be left on for at least 8 hours, then washed off with soap and water not more than 12 hours later. Re-apply Cream to hands if they are washed with soap and water within 8 hours of treatment. The following table shows how much cream should normally be used: Adults (including Elderly) and children over 12 years: Up to one tube. A few adults may need to use an additional tube, but do not apply more than two tubes. Children aged 6 to 12 years: Up to half a tube Children aged 1 to 5 years: Up to a quarter of a tube Babies aged 2 months to 1 year: Up to an eighth of a tube The dosage recommendations given in this leaflet are only intended as a guide to treatment. Because individuals can vary so much in size you might find that you need to apply slightly more or slightly less cream to completely cover the body. This will not harm you or reduce the effectiveness of the treatment.Treatment of crab lice:Not recommended for persons under 18 years of age. The elderly should be treated under medical supervision. Adults 18 years and over: Sufficient cream should be applied to cover the pubic region, peri-anal (around the anus), inner thighs down to the knees and any hair that grows up from the pubic area to the chest/stomach.One (30 g) tube is more than sufficient to treat one hairy adult. It is recommended that up to a third of a tube is used to treat the pubic region, peri-anal region, thighs, stomach and chest. Not more than two thirds of the tube should be needed for complete treatment. For relatively hair-free individuals proportionately less cream will be required.The cream should be left on the skin for 24 hours. The treatment areas should then be thoroughly washed. Any facial hair (beards, moustaches) and eyelashes should be checked for the presence of live lice and eggs. Cream should be applied to any facial hair, carefully avoiding eyes. If live lice or eggs are found on the eyelashes they should be removed carefully using tweezers. Cream should not be applied to the eye lashes because the cream can cause moderate eye irritation.
This product is able to be sourced and supplied at excellent prices because of favourable cross border currency conversions. All products are authentic brand names and will include a product information insert in English.Medical Information:Gonaphene tablets contain the active ingredient clomifene citrate (previously spelt clomiphene in the UK). (NB. Clomifene is also available without a brand name, ie as the generic medicine.)Clomifene works by causing an increase in the levels of hormones in the female body which control the development and release of an egg. These hormones are released from the pituitary gland in the brain and are known as follicle stimulating hormone (FSH) and luteinising hormone (LH). FSH stimulates the ovaries and LH causes the release of an egg from the ovaries (ovulation).Oestrogen normally causes the brain to stop releasing FSH and LH following ovulation, as part of the normal menstrual cycle. It does this by acting on receptors in a part of the brain called the hypothalamus, which sends messages to the pituitary gland.Clomifene works by blocking the oestrogen receptors in the hypothalamus. This stops oestrogen from acting on these receptors, and therefore stops the message being sent to the pituitary gland. This results in the release of more FSH and LH from the pituitary gland. The increase in these hormones increases the chances of egg development and ovulation.Clomifene is used to stimulate ovulation in women whose infertility is due to problems with ovulation.What is it used for? Infertility in women caused by failure of ovulation Atrovent Nasal Aqueous relieves the symptoms of a persistent runny nose. A runny nose is a typical symptom of the condition known as rhinitis. Rhinitis may be caused by allergies, the common cold, or other stimuli such as temperature changes or food.Atrovent Nasal Aqueous relieves a runny nose by acting directly on the mucous glands of the nose to decrease watery secretions.Atrovent Nasal Aqueous is known as an anticholinergic medicine. It belongs to one of several types of medicines used to treat the symptoms of rhinitis.How to use Atrovent NaslRead the Patient Information Leaflet provided by your pharmacist before you start using this medication and each time you get a refill. If you have any questions regarding the information, consult your doctor or pharmacist.Spray this medication in your nose, usually 2 sprays in each nostril 2 or 3 times a day as directed by your doctor. The dosage is based on your medical condition and response to therapy. Do not use ipratropium more often or for longer than prescribed.Avoid spraying in or near the eyes. If this accidentally occurs, flush your eyes with cool tap water for a few minutes. Contact of ipratropium with the eyes may cause temporary blurred vision and sensitivity to light that may last several hours. Tell your doctor immediately if you experience blurred vision or eye pain.The first time you use this medication, you must prime the bottle to make sure that the proper dose is delivered. Remove the dust cap and safety clip. Hold the bottle upright and point the tip away from your eyes. Place your thumb at the bottom of the bottle and your middle and index finger on either side of the spray tip. Press down firmly and quickly on the sprayer about 7 times until the spray appears. The device will have to be reprimed with 2 pumps if it has not been used for more than a 24 hour period. If the device is not used for more than 7 days, prime it again with 7 pumps.To use this medication, first gently blow your nose to clear the nasal passages. Tilt your head forward, close one nostril by placing a finger against the side, and gently insert the spray tip into the other nostril. Point the tip toward the back and outer side of the nostril. Squeeze the bottle to deliver the spray. Sniff deeply in through the nostril, then breathe out through your mouth. Remove the spray tip from your nose and tilt your head back for a few seconds. Deliver the second spray the same way, then repeat this procedure for the other nostril. Replace the cap and safety clip on the bottle.If the sprayer gets clogged, hold the nasal tip under warm running tap water for one minute. Dry the nasal tip, reprime, and replace the cap and safety clip.Drink a glass of water or juice after using this medication to help relieve irritated throat or bad taste in the mouth.Use this medication regularly in order to get the most benefit from it. Remember to use it at the same times each day. Although you may feel better after the first day of use, it may take up to 2 weeks before the full benefit of this drug takes effect. Indications:#All grades of essential hypertension. #Renovascular hypertension. #All degrees of heart failure. #In patients with symptomatic heart failure, m-Enalapril is also indicated to improve survival, retard the progression of heart failure and reduce hospitalisation for heart failure. #The prevention of symptomatic heart failure. #In asymptomatic patients with left ventricular dysfunction m-#Enalapril is indicated to retard development of symptomatic heart failure and reduce hospitalisation for heart failure. #Prevention of coronary ischemic events in patients with left ventricular dysfunction. #Reduce the incidence of myocardial infarction. #Reduce hospitalisation for unstable angina pectoris. Essential hypertension:The initial dose is 5mg once daily. The usual maintenance dose is 20mg once daily. The dosage should be adjusted according to the needs of the patient to a maximum of 40mg daily.Renovascular hypertension:Because blood pressure and renal function in such patients may be particularly sensitive to ACE inhibition, therapy should be initiated with a lower starting dose of 2.5mg to 5mg. The dosage should then be adjusted according to the patient's needs. Most patients may be expected to respond to one 20mg tablet taken once daily. For patients with hypertension who have been treated recently with diuretics, caution is recommended (see next paragraph).Concomitant diuretic therapy in hypertension:Symptomatic hypotension may occur following the initial dose of enalapril. This is more likely in patients who are being treated currently with diuretics. Caution is recommended as these patients may be volume or salt depleted. The diuretic therapy should be discontinued for 2-3 days prior to initiation of therapy with enalapril. If this is not possible, the initial dose of enalapril should be low (2.5mg) to determine the initial effect on the blood pressure. Dosage should then be adjusted according to the patient's needs.Heart failure/asymptomatic left ventricular dysfunction:The initial dose of enalapril in patients with symptomatic heart failure or asymptomatic left ventricular dysfunction is 2.5mg, and it should be administered under close medical supervision to determine the initial effect on the blood pressure. Enalapril may be used in the management of symptomatic heart failure usually with diuretics and, where appropriate, digitalis. In the absence of, or after effective management of, symptomatic hypotension following initiation of therapy with enalapril in heart failure, the dose should be increased gradually to the usual maintenance dose of 20mg, given in a single dose or two divided doses, as tolerated by the patient. This dose titration may be performed over a 2 to 4 week period, or more rapidly if indicated by the presence of residual signs and symptoms of heart failure. In patients with symptomatic heart failure this dosage regimen was effective in reducing mortality.Blood pressure and renal function should be monitored closely both before and after starting treatment with enalapril (see Warnings and Precautions) because hypotension and (more rarely) consequent renal failure have been reported. In patients treated with diuretics the dose should be reduced if possible, if possible, before beginning treatment with enalapril. The appearance of hypotension after the initial dose of enalapril does not imply that hypotension will recur during chronic therapy with enalapril and does not preclude continued use of the medicine. Serum potassium should also be monitored Itopride is Gastro intestinal prokinetic and it is used in the treatment of GI symptoms caused by reduced motility (Gastric fullness, Epigastric pain, anorexia, heart burn, Regurgitation, bloating, Nausea and vomitting. |
